Aluminum Meddles With Visceral Pain Perception
نویسندگان
چکیده
منابع مشابه
Purine-mediated signalling in pain and visceral perception.
Receptor subtypes for purines have been identified in a variety of tissues, increasing interest in the roles of purine-mediated signalling in pathophysiological processes. Growing evidence supports the involvement of one of the purinoceptor subtypes, P2X3, in nociception. In this article, recent studies of purine-mediated nociception and visceral pain will be discussed. Furthermore, a novel hyp...
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Visceral hypersensitivity is currently the most widely accepted mechanism responsible for abdominal pain. Inflammatory mediators are known to sensitise primary afferents and to recruit silent nociceptors. Recent evidence suggests that non-inflammatory mediators also have the potential to trigger visceral pain. This sequence of events may constitute part of an alerting system which prompts the c...
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Visceral pain, although different from somatic pain in several important features, is not as widely researched and consequently our knowledge of neurophysiologic mechanisms as well as clinical management of visceral pain states remains unsatisfactory. Several recent studies have employed different visceral pain animal models to provide insight into the peripheral and central nervous system mech...
متن کاملVISCERAL PERCEPTION Visceral perception: sensory transduction in visceral afferents and nutrients
The possible mechanisms that may be involved in nutrient detection in the wall of the gastrointestinal tract are reviewed. There is strong functional and electrophysiological evidence that both intrinsic and extrinsic primary afferent neurones mediate mechanoand chemosensitive responses in the gastrointestinal tract. This review focuses on the extrinsic afferent pathways as these are the ones t...
متن کاملMyofascial and Visceral Pain Syndromes: Visceral-Somatic Pain Representations
Objective: To describe the relationship between viscerosomatic pain syndromes and myofascial pain syndromes [MPS]. Findings: Myofascial pain syndromes can be primary conditions or secondary. When they are secondary, they occur as a manifestation of another disorder. A regional pain referral from a visceral disorder can induce secondary MPS. Visceral disorders induce central sensitization with h...
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ژورنال
عنوان ژورنال: Cellular and Molecular Gastroenterology and Hepatology
سال: 2019
ISSN: 2352-345X
DOI: 10.1016/j.jcmgh.2018.10.005